Preparation of Functionalized trans-Perhydroindans from Substituted Benzoic Acids: Reductive Alkylation-Halolactonization-Free Radical Cyclization

DOI: 10.1021/jo00249a014

Source and publish data:

Journal of Organic Chemistry p. 3210 - 3218 (1988)

Update date:2022-08-05

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Authors:

Chuang, Che-Ping

Gallucci, Judith C.

Hart, David J.

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Article abstract of DOI:10.1021/jo00249a014

Reductive alkylation of m-toluic acid (7), m-anisic acid (8), benzoic acid (9), and 2,3-dimethylbenzoic acid (31) with selected alkyl halides followed by iodolactonization and side-chain modification gave free radical precursors 13, 14, 19, 27, and 34.Tre

Full text of DOI:10.1021/jo00249a014

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