Bioorganic and Medicinal Chemistry Letters p. 1729 - 1732 (2009)
Update date:2022-07-29
Topics:
Malik, Leila
Kelly, Nicholas M.
Ma, Jian-Nong
Currier, Erika A.
Burstein, Ethan S.
Olsson, Roger
A class of small molecules displaying comparable activities with peptide ligands BAM22 and corticostatin-14 at both the human and rhesus monkey MrgX1 and MrgX2 receptors, respectively, was discovered. A comparative study to compare solid-phase and solution-phase chemistries for the efficient synthesis of the active class, tetracyclic benzimidazoles, was undertaken. The solid-phase chemistry was found to be superior both for the synthesis of analogs and for the synthesis of gram quantities.
View MoreSHENZHEN PENGCHENG REDSTAR INDUSTRY CO.,LTD
Contact:+86-755-82412922
Address:Room 8066, East Block, Square City, Jiabin Road, Luohu District
Shandong Wanda Organosilicon New Material Co., Ltd
Contact:+86-21-54177116;54302881
Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Zhejiang Allied Chemical Co.,Ltd
Contact:18967038207
Address:Area A-30, High-tech Industrial Park, Quzhou, Zhejiang, China.
JIANGXI ZHANGFENG CHEMICAL CO., LTD.
Contact:+86-0799-3413066
Address:Xiyuan village, Xiabu Town, Xiangdong District
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.
Contact:+86-750-2881198
Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
Doi:10.1016/S0040-4039(00)97448-3
(1990)Doi:10.1177/1747519820907304
(2020)Doi:10.1016/S0040-4039(00)97696-2
(1990)Doi:10.1002/hlca.19900730521
(1990)Doi:10.1021/ol200914j
(2011)Doi:10.1002/cjoc.201190083
(2011)