Organophosphorus Intermediates.X The synthesis and Properties of the 1,4-Dioxo-2,3,4a,5,6,7,8,8a-octahydro-1α5-phosphinoline System

Article abstract of DOI:10.1071/CH9871353

Addition of methyl 2-methoxycarbonylethylphosphinate to methyl cyclohexenoate followed by cyclization and hydrolysis affords a convenient route to the octahydrophosphinoline system.The reactions appear to be stereoselective and give predominantly the cis ring fused bicyclic compound.Stereochemistry is assigned largely on the basis of 13C n.m.r. spectra.Addition of methyl 2-methoxycarbonylethylphosphinate to cyclohex-2-enone and attempted cyclization of the resulting product is also reported.