
Tetrahedron Letters p. 3175 - 3178 (1988)
Update date:2022-08-03
Topics:
Snider, Barry B.
Niwa, Maho
Intramolecular cycloadditions of arylketenes 4 proceed in excellent yield to give 5-arylbicyclo<3.2.0>heptan-6-ones 5.Reaction of 5a with KOH in THF gives a 95:5 mixture of 7 and 10.Reaction of 5a with KOEt in ETOH give a 1:3 mixture of 7 and 10.Reaction of 5a with vinyllithium and treatment of the resulting alcohol 23 with KH gives the 1,3-sigmatropic rearrangement product 25.
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(1988)