
Journal of Medicinal Chemistry p. 2122 - 2126 (1988)
Update date:2022-07-29
Topics:
Mauleon
Pujol
Rosell
A series of erythro- and threo-2-(aryloxy)-1-(2-piperidyl)ethanol derivatives (3) was synthesized from 2-(2-oxiranyl)pyridine for evaluation as β-antagonists. Most compounds displayed high competitive β-blocking potency, but they lacked significant β
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