
Tetrahedron p. 4887 - 4904 (1987)
Update date:2022-08-04
Topics:
Lee, H. L.
Baggiolini, E. G.
Uskokovic, M. R.
A novel approach to D-biotin from cysteine, which utilizes the nitrile oxide to enolthioether double bond cyclization for the formation of C2-C3 of the thiophane ring and the incorporation of the 3-N in the biotin molecule, is described.The cis relation o
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