On the Synthesis of Optically Pure Monofluoro cyclohexanol Derivatives by the Fluorinated Sulfoxide Chiron Route

Article abstract of DOI:10.1016/S0040-4020(01)89545-4

Monofluorocyclohexanols 1 are obtained in optically pure form through radical cyclization of gem-chlorofluoroheptenols 2 which derive from the condensation of α-lithium derivative of sulfoxide of 3 on racemic ethyl chlorofluoroacetate 4, and hydride-promo