Heterocycles p. 1043 - 1060 (2009)
Update date:2022-07-30
Topics:
Saito, Yukako
Takahashi, Seiki
Azer, Nehad
Eldefrawi, Amira T.
Eldefrawi, Mohyee E.
Takahata, Hiroki
The asymmetric synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' has been achieved starting from 1,5-hexadiene via a common synthetic intermediate 5. The affinity of both enanthiomers of 1-4 for nicotinic acetylcholine receptor was evaluated.
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