Synthesis of chiral and achiral pyranenamine derivatives. Potent agents with topical ocular antiallergic activity

DOI: 10.1021/jm00105a060

Source and publish data:

Journal of Medicinal Chemistry p. 392 - 397 (1991)

Update date:2022-08-04

Topics:

Authors:

Gluchowski

Bischoff

Garst Garst

Kaplan Kaplan

Dietrich

Aswad Aswad

Gaffney Gaffney

Aoki Aoki

Garcia Garcia

Wheeler Wheeler

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Article abstract of DOI:10.1021/jm00105a060

The SS, RR and meso stereoisomers of pyranenamine SK and F 84210 (2) were synthesized stereospecifically starting from commercially available (R)-(-)- or (S)-(+)-2,2-dimethyl-1,3-dioxolane-4-methanol (3). In addition, two achiral pyranenamines 19 and 26 w

Full text of DOI:10.1021/jm00105a060

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