1-(3-Cyano-2,3-dideoxy-β-D-erythro-pentofuranosyl)thymine (Cyanothymidine): Synthesis and Antiviral Evaluation against Human Immunodeficiency Virus

DOI: 10.1021/jm00123a019

Source and publish data:

Journal of Medicinal Chemistry p. 618 - 622 (1989)

Update date:2022-07-29

Topics:

Authors:

Greengrass, Colin W.

Hoople, David W. T.

Street, Stephen D. A.

Hamilton, Fiona

Marriott, Michael S.

et al. et al.

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Article abstract of DOI:10.1021/jm00123a019

1-(3-Cyano-2,3-dideoxy-β-D-erythro-pentofuranosyl)thymine (cyanothymidine) (3a) has been prepared by an unambiguous route starting from D-xylose.The relative and absolute stereochemistry of 3a and its anomeric isomer 9 have been confirmed by NOE experimen

Full text of DOI:10.1021/jm00123a019

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