Application of organolithium and related reagents in synthesis. Part 15. A concise regiospecific conversion of picolinic- and isonicotinic acids into 2-benzoyl- and 4-benzoylnicotinic acids

Article abstract of DOI:10.1080/00397919408010186

The synthesis of the azaphthalides (7) and (8) and their conversion into the corresponding 2- and 4-benzoyl-3-hydroxymethylpyridines (9) and (10), very useful precursors of the 2- and 4-benzoylated nicotinic acids (11) and (12), as a way of regiospecific