ON THE STEREOSPECIFIC REDUCTION OF VINYLSULFOXIDES WITH THE POSSIBILITY OF DEUTERIUM LABELING

Article abstract of DOI:10.1016/S0040-4039(00)96914-4

Upon treating triene sulfoxide 2 or 3 in the presence of methanol (internal proton source) in ether with tert-butyllithium, the reduced product 4b or 4c, respectively, is obtaned with retention of configuration.A deuterium label can be incorporated by using methanol-d₁ as the internal proton source.