SYNTHESES OF THE METHYL GLYCOSIDES OF CURACIN, A-B FRAGMENT FOUND IN A VILAMYCIN-A AND -C, CURAMYCIN-A, FLAMBAMYCIN AND EVERNINOMICIN-2, AND OF ITS ARTIFICIAL REGIOISOMER ISOCURACIN

Article abstract of DOI:10.1016/S0040-4020(01)83453-0

Methyl 4-O-dichloroisoeverninyl-α-D-arabino-hexopyranoside, the methyl glycoside of curacin, 2, which is the chromophoric A-B terminus of orthosomycins, was synthesized by esterification of methyl 3-O-benzyl-2,6-dideoxy-α-D-arabino-hexopyranoside (9) with