Journal of Medicinal Chemistry p. 100 - 104 (1989)
Update date:2022-08-03
Topics:
Lazer, Edward S.
Wong, Hin-Chor
Possanza, Genus J.
Graham, Anne G.
Farina, Peter R.
A series of 2,6-di-tert-butyl-4-(2-arylethenyl)phenols was prepared and examined for their ability to inhibit cyclooxygenase and 5-lipoxygenase in vitro and developing adjuvant arthritis in vivo in the rat.Structure-activity relationships are discussed.Am
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