An axial-to-axial chirality transfer strategy for atroposelective construction of C–N axial chirality

Article abstract of DOI:10.1016/j.chempr.2021.04.005

C–N axially chiral skeletons are ubiquitous in bioactive natural products, pharmaceuticals, and chiral ligands. However, their atroposelective synthesis remains a formidable challenge because of their innate low configurational stability compared with tha