Synthetic Application of Tris(methylthio)methyl Salts. An Efficient Route to Trithioorthocarboxylic Esters from Strongly Activated Aromatic and Heteroaromatic Systems

Article abstract of DOI:10.1055/s-1988-27455

Nine trithioorthocarboxylic esters were synthesized by reaction of tris(methylthio)methyl methyl sulfate or tetrafluoroborate with electron-rich aromatic and heteroaromatic compounds, i.e.N,N-dialkylarylamines, pyrroles, and indoles.The new procedure is simple and offers the following advantages: easy preparation of reagents; mild reaction condition; possibility to introduce two tris(methylthio)methyl groups into the same ring, good to excellent yields.