Anchimeric Assistance of a 5'-O-Carbonyl Function for Inversion of Configuration at the 3'-Carbon Atom of 2'-Deoxyadenosine. Synthesis of 3'-Azido-2',3'-dideoxyadenosine and 3'-Azido-2',3'-dideoxyinosine

Article abstract of DOI:10.1021/jo00256a027

3'-Azido-2',3'-dideoxyadenosine was synthesized in two steps from N⁶,5'-O-dibenzoyl-2'-deoxyadenosine in 65percent yield.The configuration at the 3' position was inverted by reaction of N⁶,5'-O-dibenzoyl-2'-deoxyadenosine with trifli