Convenient synthesis of 5-substituted-6-methoxy or 6-hydroxy-2,3-dihydro-1,4-benzodioxins via lithiated intermediates

DOI: 10.1016/S0040-4020(01)90194-2

Source and publish data:

Tetrahedron p. 1421 - 1430 (1993)

Update date:2022-08-05

Topics:

Authors:

Besson Besson

Hretani Hretani

Coudert Coudert

Guillaumet

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)90194-2

The 6-methoxy and 6-tetrahydropyranyloxy-2,3-dihydro-1,4-benzodioxins can be lithiated at the 5-position to give intermediate lithio derivatives which react with various electrophiles to afford, after hydrolysis, 5-substituted-6-methoxy and 6-hydroy-2,3-d

Full text of DOI:10.1016/S0040-4020(01)90194-2

Products guided by the article

Product name:1-<5-(6-methoxy-2,3-dihydro-1,4-benzodioxinyl)>cyclohexan-1-ol

Cas No:116957-53-0

R&D Labs maybe for 116957-53-0

ShangHai BMG Chemical Co., Ltd

Contact:+86-13524845543

Address:Room 602, no 291 sikai road shanghai
taicang liyuan chemical co,.ltd

website:http://www.tcliyuanchem.com/productse.php

Contact:86-512-53539583

Address:Room 804,Huaxu Building,No.95,Renmin South Road,Taicang city,Jiangsu Province,China
KINHENG CHEMICAL(SHANGHAI)CO., LTD.

Contact:+8621-60490170

Address:Room401, No.28,Lane 189, Yangshupu Rd. Shanghai, China.
Hebei Think-Do Environment Co., Ltd

website:http://www.thinkdo-environment.com

Contact:0311-86510809-

Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Shandong Loyal Chemical industrial Co.,Ltd

Contact:0533-7451788

Address:Linzi Chemical Industrial Park, Zibo, Shandong Province

Relevant to this article

Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors

Doi:10.1021/jm301905a
(2013)
Study on the Effect of the Structure of the Leaving Group in the E1cb Mechanism of the Base-Promoted β-Elimination Reactions from N-<2-(p-Nitrophenyl)ethyl>alkylammonium Ions

Doi:10.1021/jo00131a011
(1995)
Elimination--addition. XVI. Elimination in 2-sulphonylethyl carboxylates: a method for the protection of carboxy-groups in peptide synthesis.

Doi:10.1039/j39680002612
(1968)
Doi:10.1007/BF00755276
()
Doi:10.1021/jo01263a082
(1969)
Regioselectivity of alkylation of the naphthalene fragment in the opening of a small ring in 3-ferrocenyl-3-(1-naphthyl)cyclopropene, Z-2-bromo-1-ferrocenyl-1-(1-naphthyl)cyclopropane, and 1-ferrocenyl-1-(1-naphthyl)cyclopropane

Doi:10.1016/S0022-328X(98)00755-4
(1998)

Article Doi