Convenient synthesis of 5-substituted-6-methoxy or 6-hydroxy-2,3-dihydro-1,4-benzodioxins via lithiated intermediates

DOI: 10.1016/S0040-4020(01)90194-2

Source and publish data:

Tetrahedron p. 1421 - 1430 (1993)

Update date:2022-08-05

Topics:

Authors:

Besson Besson

Hretani Hretani

Coudert Coudert

Guillaumet

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)90194-2

The 6-methoxy and 6-tetrahydropyranyloxy-2,3-dihydro-1,4-benzodioxins can be lithiated at the 5-position to give intermediate lithio derivatives which react with various electrophiles to afford, after hydrolysis, 5-substituted-6-methoxy and 6-hydroy-2,3-d

Full text of DOI:10.1016/S0040-4020(01)90194-2

Products guided by the article

Product name:1-<5-(6-methoxy-2,3-dihydro-1,4-benzodioxinyl)>cyclohexan-1-ol

Cas No:116957-53-0

R&D Labs maybe for 116957-53-0

Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai
NANCHANG QINZHI SCI&TEC.CO.,LTD(expird)

Contact:+86-13687004106

Address:Hero South Road,Hero Zone,Nanchang,Jiangxi,China
zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City
Zhangjiagang Methese Composite Material Co.,

Contact:0512-85428658

Address:Shazhou Lake Technological Innovation Park,Zhangjiagang City,Jiangsu Province,China
Hotechem Shanghai Co., Ltd

Contact:13120882795；+86-21-34621078;+86-021-31122318

Address:Suite 2,No.2715 Longwu Road

Relevant to this article

Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors

Doi:10.1021/jm301905a
(2013)
Study on the Effect of the Structure of the Leaving Group in the E1cb Mechanism of the Base-Promoted β-Elimination Reactions from N-<2-(p-Nitrophenyl)ethyl>alkylammonium Ions

Doi:10.1021/jo00131a011
(1995)
Elimination--addition. XVI. Elimination in 2-sulphonylethyl carboxylates: a method for the protection of carboxy-groups in peptide synthesis.

Doi:10.1039/j39680002612
(1968)
Doi:10.1007/BF00755276
()
Doi:10.1021/jo01263a082
(1969)
Regioselectivity of alkylation of the naphthalene fragment in the opening of a small ring in 3-ferrocenyl-3-(1-naphthyl)cyclopropene, Z-2-bromo-1-ferrocenyl-1-(1-naphthyl)cyclopropane, and 1-ferrocenyl-1-(1-naphthyl)cyclopropane

Doi:10.1016/S0022-328X(98)00755-4
(1998)

Article Doi