Design and synthesis of DNA cleaving bleomycin models: 1,2-trans- disubstituted cyclopropane units as novel linkers

DOI: 10.1016/S0040-4039(00)73490-3

Source and publish data:

Tetrahedron Letters p. 5323 - 5326 (1994)

Update date:2022-08-05

Topics:

Authors:

Huang Huang

Quada Jr.

Lown Lown

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73490-3

The design and synthesis of 1a - e, functional models for bleomycin are described in which AMPHIS, a metal-complexing model of bleomycin, and a distamycin moiety are connected with a series of linkers. Studies on the rates of DNA breakage and a mobility a

Full text of DOI:10.1016/S0040-4039(00)73490-3

Products guided by the article

Product name:((R)-1-{[(2-Benzyloxycarbonylamino-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-carbamic acid tert-butyl ester

Cas No:117233-64-4

R&D Labs maybe for 117233-64-4

Shanghai Hanhong Scientific Co.,Ltd.

website:http://www.chemvia.com

Contact:+86-21-64541543,54280654,13918533501

Address:Jiachuan Road 245
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Rudong Zhenfeng Yiyang Chemical Co., Ltd.

Contact:0513-84573047

Address:South Fengli Town, Rudong County, Jiangsu Province, China
Changsha Easchem Co.,Limited

website:http://www.easchem.com

Contact:+86-731-89722861 89722891

Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
HEBEI BRANT PHARMACEUTICAL

Contact:+86-0311-84455288-844

Address:Mayu Industrial Park, Jinzhou, Hebei, China.

Relevant to this article

1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2)

Doi:10.1016/j.bmcl.2016.07.031
(2016)
Modification of 2-amino-4-phenylthiazole under microwave irradiation

Doi:10.1134/S1070363209030311
(2009)
A Facile Entry to the 2-Azabicyclo<2.2.2>octane-6-one Skeleton via <4 + 2>-Cycloaddition

Doi:10.1055/s-1988-27472
(1988)
10-Ethyl-4-oxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinolin-2-iminium 4-toluenesulfonate: A polarized electronic structure in the cation and a hydrogen-bonded sheet structure

Doi:10.1107/S0108270108016995
(2008)
A new way for synthetizing (E)-methyl methylsulfanyl(phenylamino)methylene carbamates via Beckmann transposition in triflic acid

Doi:10.4314/bcse.v29i2.11
(2015)
NH₂SO₃H and H₆P₂W ₁₈O₆₂18H₂O-catalyzed, three-component, one-pot synthesis of benzo[ c[acridine derivatives

Doi:10.1080/00397911.2010.550704
(2012)

Article Doi