Design and synthesis of DNA cleaving bleomycin models: 1,2-trans- disubstituted cyclopropane units as novel linkers

DOI: 10.1016/S0040-4039(00)73490-3

Source and publish data:

Tetrahedron Letters p. 5323 - 5326 (1994)

Update date:2022-08-05

Topics:

Authors:

Huang Huang

Quada Jr.

Lown Lown

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73490-3

The design and synthesis of 1a - e, functional models for bleomycin are described in which AMPHIS, a metal-complexing model of bleomycin, and a distamycin moiety are connected with a series of linkers. Studies on the rates of DNA breakage and a mobility a

Full text of DOI:10.1016/S0040-4039(00)73490-3

Products guided by the article

Product name:((R)-1-{[(2-Benzyloxycarbonylamino-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-carbamic acid tert-butyl ester

Cas No:117233-64-4

R&D Labs maybe for 117233-64-4

SHIJIAZHUANG HENRYTE CHEMICALS CO,.LTD(expird)

Contact:+86-311-85208698 311-80837698

Address:NO.166, yuhua west road, SHIJIAZHUANG, China
Hangzhou Zhenghan Biological Technology Co., Ltd.

Contact:86-571-88781753

Address:liangzhu yuhang hangzhou city
Ningbo J&S Botanics Inc.

Contact:86-574-26865651

Address:529 YuanBaoShan Road, Beilun District
Phytomarker Ltd.(expird)

Contact:+86-22-26358246

Address:601-4-20, Fujiayuan, Tiantai Road, Hebei District, Tianjin, China
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-39971718

Address:859 jiadingchengliu shanghai

Relevant to this article

1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2)

Doi:10.1016/j.bmcl.2016.07.031
(2016)
Modification of 2-amino-4-phenylthiazole under microwave irradiation

Doi:10.1134/S1070363209030311
(2009)
A Facile Entry to the 2-Azabicyclo<2.2.2>octane-6-one Skeleton via <4 + 2>-Cycloaddition

Doi:10.1055/s-1988-27472
(1988)
10-Ethyl-4-oxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinolin-2-iminium 4-toluenesulfonate: A polarized electronic structure in the cation and a hydrogen-bonded sheet structure

Doi:10.1107/S0108270108016995
(2008)
A new way for synthetizing (E)-methyl methylsulfanyl(phenylamino)methylene carbamates via Beckmann transposition in triflic acid

Doi:10.4314/bcse.v29i2.11
(2015)
NH₂SO₃H and H₆P₂W ₁₈O₆₂18H₂O-catalyzed, three-component, one-pot synthesis of benzo[ c[acridine derivatives

Doi:10.1080/00397911.2010.550704
(2012)

Article Doi