Bioorganic and Medicinal Chemistry Letters p. 2251 - 2254 (1997)
Update date:2022-08-03
Topics: Characterization Deprotection Isolation and Purification Starting Material Protection of Hydroxyl Groups Protection of the Amino Group
Sofia, Michael J.
Kakarla, Ramesh
Kogan, Natan
Dulina, Richard
Hui
Hatzenbuhler, Nicole T.
Liu, Dashan
Chen, Anna
Wagler, Thomas
The drug transport reagent, methyl 3-β-amino-7α, 12α-di(1'α-glucosyl)-5β-cholate (TC002) 1 was prepared in 15% overall yield from pentaacetyl glucose and methyl cholate. Pentaacetyl glucose was converted to glucosyl sulfoxide 2 in 56% overall yield. Methyl cholate was converted to methyl 3-β-azido cholate 3 in 67% yield. Bis-glycosylation of 3 with 2 followed by a single step reduction provided 1.
View Morewebsite:http://www.mingchem.com/en/index
Contact:0519-85170101-802
Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Dayang Chem (Hangzhou) Co.,Ltd.
website:http://www.dycnchem.com
Contact:+86-571-88938639
Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China
Shanghai shibo Chemical Co., Ltd
Contact:+86-021-60753516
Address:688 Qiushi Road, Jinshan High-tech Park, Shanghai, China,201512
Hunan Haili Chemical Industry Co.,Ltd.
Contact:+86-731-85521860
Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Shandong Hongxiang Zinc Co., Ltd
Contact:086-0311-66187879
Address:DaWang developing zone
Doi:10.1016/j.bmc.2009.04.018
(2009)Doi:10.1016/j.ejmech.2010.01.044
(2010)Doi:10.1002/anie.201906978
(2019)Doi:10.1039/b903878g
(2009)Doi:10.1021/jo501162s
(2014)Doi:10.1016/j.tetlet.2009.05.086
(2009)
