SYNTHESIS OF A NON-ISOSTERIC, ISOPOLAR MONOPHOSPHONATE ANALOGUE OF β-D-FRUCTOSE 2,6-BISPHOSPHATE

Article abstract of DOI:10.1016/0008-6215(88)85080-8

A synthesis of the non-isosteric, isopolar glyculosylmonophosphonate analogue 6 of β-D-fructose 2,6-bisphosphate (1) is described.Treatment of 2-O-acetyl-1,3,4,6-tetra-O-benzyl-α,β-D-fructofuranose (8) with trialkyl or triaryl phosphite in the presence of