Potent Angiotensin II Antagonists with Non-β-branched Aminoacids in Position 5

DOI: 10.1021/jm00122a030

Source and publish data:

Journal of Medicinal Chemistry p. 466 - 472 (1989)

Update date:2022-08-05

Topics:

Authors:

Samanen, J.

Narindray, D.

Cash, T.

Brandeis, E.

Adams, W.

et al. et al.

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Article abstract of DOI:10.1021/jm00122a030

Amino acids with lipophilic side chains that contain more than one functional group on the β-carbon, i.e. a β-branched hydrocarbon moiety, are required in position 5 of angiotensin II (AII) analogue with potent agonist activity.This requirement for agonis

Full text of DOI:10.1021/jm00122a030

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