Abnormal Ring Opening of 1,2-Epoxyalkyldiphenylphosphine Oxides with Lithium Aluminum Hydride to Form 2-Hydroxyalkyldiphenylphosphine Oxides

Article abstract of DOI:10.1055/s-1988-27557

Ring opening of 1,2-epoxyalkyldiphenylphosphine oxides with LiAlH4 gives 2-hydroxyalkyldiphenylphosphine oxides in good yield.This is the first example of ring opening of 1,2-epoxyalkyldiphenylphosphine oxides to give the corresponding 2-hydroxy derivativ