Synlett p. 1575 - 1578 (2009)
Update date:2022-09-26
Topics:
Adib, Mehdi
Kesheh, Mahdi Riazati
Ansari, Samira
Bijanzadeh, Hamid Reza
A one-pot and three-component synthesis of 2-aryl-5-hydroxyalkyl-1,3,4- oxadiazoles is described. N-Isocyaniminotriphenylphosphorane, an aldehyde, and a carboxylic acid undergo a 1:1:1 addition reaction under mild conditions to afford the title compounds
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(2009)