Chemistry Letters p. 524 - 525 (2009)
Update date:2022-07-30
Topics:
Mori, Keiji
Ohshima, Yoshitaka
Ehara, Kensuke
Akiyama, Takahiko
A simple method for the synthesis of quinazolines was developed by exploiting the "tert-amino effect." A catalytic amount of Br0nsted acid (TsOH·H2O) worked as an effective activator for the concise construction of a quinazoline framework from o-formylaniline and amine. Copyright
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