Tetrahedron Letters p. 2577 - 2580 (1988)
Update date:2022-08-04
Topics:
Iqbal, Zafar
Jackson, Anthony H.
Nagaraja Rao, K. R.
Indoles react with αβ-unsaturated carbonyl compounds in the presence of clay catalysts to give substituted indoles in good yields; in one case a 3-benzyl substituent already present migrated to the 2-position, being displaced by the incoming electrophile, thus confirming that electrophilic substitution in indole occurs primarily at the 3-position.
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(1988)
