SYNTHESIS OF NITROGEN HETEROCYCLES VIA PALLADIUM-CATALYZED INTRAMOLECULAR CYCLIZATION

DOI: 10.1016/S0040-4039(00)96710-8

Source and publish data:

Tetrahedron Letters p. 5291 - 5294 (1987)

Update date:2022-07-30

Topics:

Authors:

Larock, Richard C.

Babu, Srinivasan

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Article abstract of DOI:10.1016/S0040-4039(00)96710-8

Catalytic amounts of Pd(OAc)2 in the presence of n-Bu4NCl, DMF and an appropriate base (Na2CO3, NaOAc or Et3N) cyclize nitrogen-containing o-iodoaryl alkenes to indoles, indolines, oxindoles, quinolines, isoquinolines and isoquinolones in short reaction times, under mild temperatures, and in high yields.

Full text of DOI:10.1016/S0040-4039(00)96710-8

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