A2Badenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives

DOI: 10.1016/j.ejmech.2016.11.007

Source and publish data:

European Journal of Medicinal Chemistry p. 986 - 996 (2017)

Update date:2022-08-04

Topics:

Authors:

Basu, Sujay

Barawkar, Dinesh A.

Ramdas, Vidya

Waman, Yogesh

Patel, Meena

Panmand, Anil

Kumar, Santosh

Thorat, Sachin

Bonagiri, Rajesh

Jadhav, Dilip

Mukhopadhyay, Partha

Prasad, Vandna

Reddy, B. Srinivasa

Goswami, Arnab

Chaturvedi, Sandhya

Menon, Suraj

Quraishi, Azfar

Ghosh, Indraneel

Dusange, Sushant

Paliwal, Shalini

Kulkarni, Abhay

Karande, Vikas

Thakre, Rhishikesh

Bedse, Gaurav

Rouduri, Sreekanth

Gundu, Jayasagar

Palle, Venkata P.

Chugh, Anita

Mookhtiar, Kasim A.

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Article abstract of DOI:10.1016/j.ejmech.2016.11.007

A_2BAdoR is a low affinity adenosine receptor that functions by Gs mediated elevation of cAMP and subsequent downstream signaling. The receptor has been implicated in lung inflammatory disorders like?COPD and asthma. Several potent and selective

Full text of DOI:10.1016/j.ejmech.2016.11.007

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