A2Badenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives

DOI: 10.1016/j.ejmech.2016.11.007

Source and publish data:

European Journal of Medicinal Chemistry p. 986 - 996 (2017)

Update date:2022-08-04

Topics:

Authors:

Basu, Sujay

Barawkar, Dinesh A.

Ramdas, Vidya

Waman, Yogesh

Patel, Meena

Panmand, Anil

Kumar, Santosh

Thorat, Sachin

Bonagiri, Rajesh

Jadhav, Dilip

Mukhopadhyay, Partha

Prasad, Vandna

Reddy, B. Srinivasa

Goswami, Arnab

Chaturvedi, Sandhya

Menon, Suraj

Quraishi, Azfar

Ghosh, Indraneel

Dusange, Sushant

Paliwal, Shalini

Kulkarni, Abhay

Karande, Vikas

Thakre, Rhishikesh

Bedse, Gaurav

Rouduri, Sreekanth

Gundu, Jayasagar

Palle, Venkata P.

Chugh, Anita

Mookhtiar, Kasim A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.ejmech.2016.11.007

A_2BAdoR is a low affinity adenosine receptor that functions by Gs mediated elevation of cAMP and subsequent downstream signaling. The receptor has been implicated in lung inflammatory disorders like?COPD and asthma. Several potent and selective

Full text of DOI:10.1016/j.ejmech.2016.11.007

Products guided by the article

Product name:8-(1-{2-hydroxy-2-[5-oxo-1-(3-trifluoromethylphenyl)pyrrolidin-3-yl]ethyl}-1H-pyrazol-4-yl)-1,3-dipropyl-3,7-dihydropurine-2,6-dione

Cas No:1188543-10-3

R&D Labs maybe for 1188543-10-3

Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-62886900

Address:Keji Road NO.70
SHANGHAI ARCADIA BIOTECHNOLOGY LTD.

Contact:+86-21-61353236

Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA
Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road
APOLLO HEALTHCARE RESOURCES

Contact:+65 9658 0999

Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
Nanjing yieldpharma co.ltd

Contact:13813902930 025-52714267

Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China

Relevant to this article

Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA_A receptors

Doi:10.1016/j.bmc.2010.11.050
(2011)
Synthesis, characterization, cytotoxicity, and molecular docking studies of ampyrone-based transition metal complexes

Doi:10.1007/s11243-020-00422-8
(2021)
Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity

Doi:10.1016/j.bmc.2009.05.075
(2009)
Synthesis of new 1, 4-Dihydropyridines by addition-rearrangement process with imine derivatives and β-Ketoester as starting materials in solvent-free conditions

Doi:10.2174/157017809787893082
(2009)
Investigation of piperazine benzamides as human β₃ adrenergic receptor agonists for the treatment of overactive bladder

Doi:10.1016/j.bmcl.2016.12.033
(2017)
Synthesis of 1-aryl-1,2,3 triazole-4,5-dimethanol-4,5-bis (isopropylcarbamates) as potential antineoplastic agents

Doi:10.1002/jhet.5570270338
(1990)

Article Doi