Inositol monophosphates prepared in a single step from myo-inositol and inorganic phosphate

Article abstract of DOI:10.1080/07328300008544076

A mixture of myo-inositol and inorganic metaphosphate (prepared by freeze drying an aqueous solution at pH 4) produced, upon warming, in moderate yield every inositol monophosphate ester, thereby providing in a single step a complete library of these compounds. The individual inositol monophosphates, both meso-compounds and racemic mixtures of the two pairs of enantiomers, were isolated by ion-exchange chromatography which was facilitated by the addition of borate to the mobile phase. The phosphates were characterised using phosphorus analysis in conjunction with alkaline phosphatase, mass spectrometry and ¹H NMR spectroscopy.

Full text of DOI:10.1080/07328300008544076

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Journal of Carbohydrate Chemistry
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Inositol Monophosphates Prepared in
a Single Step from Myo-Inositol and
Inorganic Phosphate
Edward Tarelli
a The Joint Microbiology Research Unit, Kings College School
of Medicine and Dentistry, Caldecot Road, Denmark Hill.
London SE5 9RW, UK
Published online: 27 Feb 2008.
To cite this article: Edward Tarelli (2000): Inositol Monophosphates Prepared in a Single Step
from Myo-Inositol and Inorganic Phosphate, Journal of Carbohydrate Chemistry, 19:2, 233-241
To link to this article: http://dx.doi.org/10.1080/07328300008544076
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