
Chemical and Pharmaceutical Bulletin p. 252 - 254 (1992)
Update date:2022-08-02
Topics:
Fukuyama
Hasegawa
Toda
Kodama
Okazaki
The structures of new neo-lignans, isoamericanol A (1) and americanol A (2) isolated from the seeds of Phytolacca americana have been elucidated on the basis of spectroscopic data and then confirmed by chemical correlation with the previouslty known isoamericanin A (3) and americanin A (4). Isoamericanol A, americanol A, and americanin A have been found to enhance choline acetyltransferase activity at 10-5 M in a cultured neuronal cell system derived from fetal rat hemisphere.
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