Synthesis and biological evaluation of certain C-4 substituted pyrazolo[3,4-b]pyridine nucleosides

Article abstract of DOI:10.1021/jm00125a004

A series of C-4 substituted pyrazolo[3,4-b]pyridine nucleosides have been synthesized and evaluated for their biological activity. Successful synthesis of various C-4 substituted pyrazolo[3,4-b]pyridine nucleosides involves nucleophilic displacement by a