The Role of the 2-Methyl Substituent in Governing Stereoselective Formation of the E Isomer in the Synthesis of 4-Hydroxy-2-methyltamoxifen (1-phenyl>-1-(4-hydroxy-2-methylphenyl)-2-phenylbut-1-ene)

DOI: 10.1039/P29880001201

Source and publish data:

Journal of the Chemical Society. Perkin transactions II p. 1201 - 1208 (1988)

Update date:2022-08-05

Topics:

Authors:

McCague, Raymond

Leung, On-Tai

Jarman, Michael

Kuroda, Reiko

Neidle, Stephen

Webster, Gordon

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P29880001201

Syntheses of 4-hydroxy-2-methyltamoxifen (1-<4-<2-(dimethylamino)ethoxy>phenyl>-1-(4-hydroxy-2-methylphenyl)-2-phenylbut-1-ene) by dehydration of diastereoisomeric triphenylbutan-1-ol precursors were compared.Crystal structures of these diastereoisomers h

Full text of DOI:10.1039/P29880001201

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:1-(4-methoxyphenyl)-1-(4-methoxy-2-methylphenyl)-2-phenyl-(E)-but-1-ene

Cas No:119405-25-3

R&D Labs maybe for 119405-25-3

Wuxi Pharma-Trading Import & Export Co.,Ltd.

Contact:+86-510-82304590 82716390

Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
Daicel Chiral Technologies (China)CO.,LTD

Contact:021-5046-0086*8

Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
Suzhou Sibian Chemical Technology Co., Ltd

website:http://www.sibianpharm.com

Contact:+8618169181984,+8618013186906

Address:Room1404,BuildingA,Jiabao Square No.323 Baodai East Road,Wuzhong District,Suzhou Jiangsu China (215128)
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
Hangzhou Haichem Co.,Ltd.

Contact:+86-571-86025531 / 86024803

Address:1218-24 Guangyin Mansion,42 Fengqi East Road

Relevant to this article

Doi:10.1021/jo01086a018
(1959)
Ruthenium-catalyzed hydrogenation of nitriles: Insights into the mechanism

Doi:10.1021/ja102759z
(2010)
Exploration of novel 2-alkylimino-1,3-thiazolines: T-type calcium channel inhibitory activity

Doi:10.1021/cc100041m
(2010)
Solid-state ¹¹⁵In and ³¹P NMR studies of triarylphosphine indium trihalide adducts

Doi:10.1021/ja100625p
(2010)
Synthesis, antiprolife ativeactivity and inhibition of tubulinpolymerization by 1,5-and 1,8-disubstituted 10H-anthracen-9-onesbearinga 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety

Doi:10.1016/j.ejmech.2010.04.032
(2010)
Uses of metallacyclobutenes in heterocyclic synthesis. Synthesis and structural characterization of 1,2-dihydrophosphetes

Doi:10.1021/ja00207a035
(1989)

Article Doi