Bioorganic and Medicinal Chemistry Letters p. 5613 - 5616 (2009)
Update date:2022-08-04
Topics:
Guo, Chuangxing
Hou, Xinjun
Dong, Liming
Dagostino, Eleanor
Greasley, Samantha
Ferre, RoseAnn
Marakovits, Joseph
Johnson, M. Catherine
Matthews, David
Mroczkowski, Barbara
Parge, Hans
VanArsdale, Todd
Popoff, Ian
Piraino, Joseph
Margosiak, Stephen
Thomson, James
Los, Gerrit
Murray, Brion W.
Pin1 is a member of the cis-trans peptidyl-prolyl isomerase family with potential anti-cancer therapeutic value. Here we report structure-based de novo design and optimization of novel Pin1 inhibitors. Without a viable lead from internal screenings, we de
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Doi:10.1055/s-0029-1217708
(2009)Doi:10.1021/jm9010687
(2009)Doi:10.1002/ejoc.200900800
(2009)Doi:10.1021/ja9076588
(2009)Doi:10.1039/b914802g
(2009)Doi:10.1021/ic901579u
(2009)
