Efficient Synthesis of 5,5-Dialkyl-Δ1-1,2,4-triazolin-3-ones by Acid Hydrolysis of Bis(α-isocyanatoalkyl)diazenes

Article abstract of DOI:10.1055/s-1987-28143

The hydrolysis of bis(α-isocyanatoalkyl)diazenes with hydrochloric acid affords the novel 5,5-dialkyl-Δ¹-1,2,4-triazolin-3-ones in good yields, and as a minor by-product, the corresponding 4-aminocarbonyl derivatives.The 1,2,4-triazolin-3-ones are easily converted into the 4-benzoyl derivatives which, in turn, react as mild benzoylating agents toward primary amines.