Tetrahedron Letters p. 6957 - 6960 (1988)
Update date:2022-07-29
Topics:
Ohta, Hiromichi
Kimura,Yoichi
Sugano, Yasushi
Incubation of dl-1-cyano-1-metylalkyl (or alkenyl) acatates (methyl ketone cyanohydrin acetates) with cells of Pichia miso IAM 4682 afforded optically active acetates and the corresponding ketones via asymmetric hydrolysis.Resulting (S)-2-cyano-2-undecyl acetate was converted to the aminofuranone derivative without losing its optical purity.
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