Cram's Rule for Radical Reactions

DOI: 10.1016/0040-4039(91)80762-U

Source and publish data:

Tetrahedron Letters p. 6097 - 6100 (1991)

Update date:2022-08-03

Topics:

Authors:

Giese, Bernd

Damm, Wolfgang

Dickhaut, Joachim

Wetterich, Frank

Sun, Shunneng

Curran, Dennis P.

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Article abstract of DOI:10.1016/0040-4039(91)80762-U

Addition of tris(trimethylsilyl)silyl radicals to chiral ketones 1 yields tert. carbon centered radicals 4 that give predominantly Cram products in hydrogen atom abstraction reactions.Analogous sec. acyloxyalkyl radicals undergo radical C,D- and C,C-bond forming reactions that also follow Cram's rule.

Full text of DOI:10.1016/0040-4039(91)80762-U

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