SYNTHESIS OF THE POTENT POTASSIUM CHANNEL OPENER Ro 31-6930 VIA CLAISEN REARRANGEMENT AND TANDEM REGIOCONTROLLED CYCLISATION.

DOI: 10.1016/S0040-4039(00)74894-5

Source and publish data:

Tetrahedron Letters p. 811 - 814 (1991)

Update date:2022-08-04

Topics:

Authors:

Attwood, Michael R.

Churcher, Ian

Dunsdon, Rachel M.

Hurst, David N.

Jones, Philip S.

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Article abstract of DOI:10.1016/S0040-4039(00)74894-5

The synthesis of the potent potassium channel opener Ro 31-6930 is reported.Methods of controlling the regiochemistry of the crucial cyclisation are described.

Full text of DOI:10.1016/S0040-4039(00)74894-5

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