Journal of Organic Chemistry p. 5121 - 5129 (1993)
Update date:2022-08-04
Topics:
Arai, Masayuki
Kawasuji, Takashi
Nakamura, Eiichi
The SN2'-selective reaction of organocopper or organizinc reagents with allylic chlorides having a chiral center at the δ-position proceeds with up to 100percent diastereoselectivity.The observed 1,2-asymmetric induction conforms to pure steric control (Cram-Felkin-Anh model) even in cases where conventional chelation control may seem to operate, and the level of the selectivity was found to be much higher than those found for the additions of organometallics to structurally comparable α-substituted carbonyl compounds.
View MoreGeen Chemical Technology Co., Ltd
Contact:86-769-21660847
Address:1408, Yingfeng Commercial Center, Nancheng District
JIN TAN CHENG'EN CHEMICAL CO.,LTD.
Contact:86-519-82116250
Address:NO.102,village Dongfang,conomic development zone
Yancheng Smiling Imp & Exp Co., Ltd.
Contact:+86-515-83173586
Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Wuhan Chemchemical Co., Ltd.(expird)
Contact:15973022782
Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Doi:10.1021/jm7009952
(2008)Doi:10.1007/s00044-007-9001-3
(2007)Doi:10.1002/ardp.19592920303
(1959)Doi:10.1002/ardp.201300202
(2013)Doi:10.1021/jm070639e
(2007)Doi:10.1016/j.bmcl.2010.04.020
(2010)