Synthesis and Reactions of Isoquinoline Derivatives III. Synthesis and Reactions of 3,4-Dihalogeno-1-phenylisoquinolines

DOI: 10.1055/s-1988-27670

Source and publish data:

Synthesis p. 683 - 685 (1988)

Update date:2022-08-04

Topics:

Authors:

Renger, B.

Konz, E.

Rueger, W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1988-27670

Reaction of 1-phenyl-1,4-dihydro-3(2H)isoquinolinone (1) with phosphorus pentahalides as well as a two-step procedure involving a Vilsmeier-Haack acylation of 1 followed by oxidative cleavage with sodium hypohalites make 3,4-dihalogeno-1-phenylisoquinolines easily available.

Full text of DOI:10.1055/s-1988-27670

Products guided by the article

Product name:4-Bromo-3-chloro-1-phenylisoquinoline

Cas No:120285-05-4

R&D Labs maybe for 120285-05-4

New Forms

Contact:+31-24-3886056

Address:Binderskampweg 29 Unit 36
Shanggao Ruiya Fine Chemicals Co., Ltd

Contact:+86-795-2592103

Address:Xingguang Nanlu,Shanggao County Industry Park
Shenzhen JYMed Technology Co.,Ltd.

website:http://www.jymedtech.com

Contact:+86-755-26612112

Address:1#8,9/F, Biomedicine innovation Industrial Park, No.14, Jinhui Road, Pingshan Sistrict, Shenzhen, China
Nantong Baokai Chemical Co., Ltd (Hangzhou Baokai Bio-Chemicals Co.,Ltd.)

Contact:+86-513-83886111

Address:No. 68 Suzhou road ,Binjiang Fine Chemical Industrial Park , Beixin town, Qidong city ,Jiangsu province
Nantong Baokai Chemical Co., Ltd (Hangzhou Baokai Bio-Chemicals Co.,Ltd.)

Contact:+86-513-83886111

Address:No. 68 Suzhou road ,Binjiang Fine Chemical Industrial Park , Beixin town, Qidong city ,Jiangsu province

Relevant to this article

High-performance liquid chromatographic enantiomer separation and determination of absolute configurations of phosphinic acid analogues of dipeptides and their α-aminophosphinic acid precursors

Doi:10.1016/S0957-4166(03)00537-8
(2003)
The Unusually Slow Hydrolysis Rate of Silyl Methyl Ketals in Benzoquinone Systems. The Question of Siloxy Stabilization of an Adjacent Positive Charge and Stereoelectronic Effects on Ketal Hydrolysis

Doi:10.1021/jo00273a033
(1989)
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms

Doi:10.1016/j.bmcl.2016.07.041
(2016)
Reactivity of a propiolate dimer with nucleophiles and an efficient synthesis of dimethyl α-aminoadipate

Doi:10.1016/j.tetlet.2009.11.048
(2010)
Palladium(II)-catalyzed oxidative ortho -arylation of 2-phenylpyridines

Doi:10.1055/s-0033-1339516
(2013)
Studies on new catechol containing cephalosporins. III. Synthesis and structure-activity relationships of cephalosporins having a pyridone moiety at the C-7 position

Doi:10.7164/antibiotics.50.279
(1997)

Article Doi