Synthesis and Reactions of Isoquinoline Derivatives III. Synthesis and Reactions of 3,4-Dihalogeno-1-phenylisoquinolines

DOI: 10.1055/s-1988-27670

Source and publish data:

Synthesis p. 683 - 685 (1988)

Update date:2022-08-04

Topics:

Authors:

Renger, B.

Konz, E.

Rueger, W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1988-27670

Reaction of 1-phenyl-1,4-dihydro-3(2H)isoquinolinone (1) with phosphorus pentahalides as well as a two-step procedure involving a Vilsmeier-Haack acylation of 1 followed by oxidative cleavage with sodium hypohalites make 3,4-dihalogeno-1-phenylisoquinolines easily available.

Full text of DOI:10.1055/s-1988-27670

Products guided by the article

Product name:4-Bromo-3-chloro-1-phenylisoquinoline

Cas No:120285-05-4

R&D Labs maybe for 120285-05-4

Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-88211911

Address:Keji Road NO.70
Tianjin Te-An Chemtech Co., Ltd.(expird)

Contact:+86-22-65378638

Address:A5-8, No.80 Haiyun Street, TEDA
Shanghai HengXun Pharmaceutical Tech. Co., Ltd.

Contact:86-86-52730756

Address:Room 603, No. 240, Tianmuzhong Road, Zhabei, Shanghai, China
Zhenjiang Huayu I/E Co.,LTD

Contact:86-511-85210668 0511-85210668, 85210818, 85210898

Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
Tianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)

Contact:+86-22-66211386

Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457

Relevant to this article

High-performance liquid chromatographic enantiomer separation and determination of absolute configurations of phosphinic acid analogues of dipeptides and their α-aminophosphinic acid precursors

Doi:10.1016/S0957-4166(03)00537-8
(2003)
The Unusually Slow Hydrolysis Rate of Silyl Methyl Ketals in Benzoquinone Systems. The Question of Siloxy Stabilization of an Adjacent Positive Charge and Stereoelectronic Effects on Ketal Hydrolysis

Doi:10.1021/jo00273a033
(1989)
New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms

Doi:10.1016/j.bmcl.2016.07.041
(2016)
Reactivity of a propiolate dimer with nucleophiles and an efficient synthesis of dimethyl α-aminoadipate

Doi:10.1016/j.tetlet.2009.11.048
(2010)
Palladium(II)-catalyzed oxidative ortho -arylation of 2-phenylpyridines

Doi:10.1055/s-0033-1339516
(2013)
Studies on new catechol containing cephalosporins. III. Synthesis and structure-activity relationships of cephalosporins having a pyridone moiety at the C-7 position

Doi:10.7164/antibiotics.50.279
(1997)

Article Doi