Synthetic Communications p. 1191 - 1198 (1992)
Update date:2022-08-05
Topics:
Nagarajan
Ho
DuBois
A simple method for the synthesis of sweet tasting N, N', N''-trisubstituted guanidines is described. The key intermediate, carbonimidoyl dichloride 6, was prepared using a known method. Reaction fo 6 with cyclooctylamine followed by the sodium salt of 5-
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