ASYMMETRIC SYNTHESIS trans-β-LACTAMS THROUGH TiCl4-MEDIATED ADDITION TO IMINES.

DOI: 10.1016/S0040-4039(00)95693-4

Source and publish data:

Tetrahedron Letters p. 227 - 230 (1987)

Update date:2022-08-04

Topics:

Authors:

Gennari, Cesare

Venturini, Isabella

Gislon, Gabriele

Schimperna, Giuliana

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)95693-4

TiCl4-mediated addition of the chiral silyl ketene acetal (2) to benzylideneaniline proceeds with high stereoselectivity to give, after cyclization, trans-β-lactam (7) in good yield and 95percent e.e.

Full text of DOI:10.1016/S0040-4039(00)95693-4

Products guided by the article

Product name:(2R,3S)-2-Methyl-3-phenyl-3-phenylamino-propionic acid (1S,2R)-2-dimethylamino-1-phenyl-propyl ester

Cas No:120521-18-8

R&D Labs maybe for 120521-18-8

SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue
Shenzhen Sunrising Industry Co., ltd.

Contact:+86 755 86571158 / 86571159 / 86571160

Address:2108 ZHENYE INT. BUSINESS CENTER,NO.3101-90 QIANHAI RD, NANSHAN,SHENZHEN, CHINA
Chengdu Baishixing Science and Technology Industry Co., Ltd.

website:http://www.cd-bsx.com

Contact:+86-28-88531548

Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
Jiaxing Carry Bio-Chem Technology Co.,Ltd

website:http://www.carrybiotech.com

Contact:0573-82788958

Address:Add.Fl 3th, Pharm Vally,Kaichuang Rd, Xiuzhou District, Jiaxing, Zhejiang,314031,China
Shandong Loyal Chemical industrial Co.,Ltd

Contact:0533-7451788

Address:Linzi Chemical Industrial Park, Zibo, Shandong Province

Relevant to this article

Ligand-Dependent Site-Selective Suzuki Cross-Coupling of 4-Bromopyrazol-5-yl Triflates

Doi:10.1021/acs.joc.9b01306
(2019)
Rearrangement of oxazolidinethiones to thiazolidinediones or thiazinanediones and their application for the synthesis of chiral allylic ureas and α-methyl-β-amino acids

Doi:10.1016/j.tet.2009.11.035
(2010)
Highly Selective Formation of Cis-Substituted Hydroxylactams via Auxiliary-Controlled Reduction of Imides

Doi:10.1021/jo00272a004
(1989)
Liquid-crystalline self-organization of isocyanide-containing dendrimers induced by coordination to gold(I) fragments

Doi:10.1021/ja909435e
(2010)
Copper-catalyzed addition of water affording highly substituted furan and unusual formation of naphthofuran ring from 3-(1-alkenyl)-2-alkene-1-al

Doi:10.1016/j.tetlet.2009.10.125
(2010)
New chromane-based derivatives as inhibitors of mycobacterium tuberculosis salicylate synthase (mbti): Preliminary biological evaluation and molecular modeling studies

Doi:10.3390/molecules23071506
(2018)

Article Doi