ASYMMETRIC SYNTHESIS trans-β-LACTAMS THROUGH TiCl4-MEDIATED ADDITION TO IMINES.

DOI: 10.1016/S0040-4039(00)95693-4

Source and publish data:

Tetrahedron Letters p. 227 - 230 (1987)

Update date:2022-08-04

Topics:

Authors:

Gennari, Cesare

Venturini, Isabella

Gislon, Gabriele

Schimperna, Giuliana

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)95693-4

TiCl4-mediated addition of the chiral silyl ketene acetal (2) to benzylideneaniline proceeds with high stereoselectivity to give, after cyclization, trans-β-lactam (7) in good yield and 95percent e.e.

Full text of DOI:10.1016/S0040-4039(00)95693-4

Products guided by the article

Product name:(2R,3S)-2-Methyl-3-phenyl-3-phenylamino-propionic acid (1S,2R)-2-dimethylamino-1-phenyl-propyl ester

Cas No:120521-18-8

R&D Labs maybe for 120521-18-8

Basilea Pharmaceutica China Ltd.

Contact:+86-513-82198075

Address:No.638 Xiushan Road(East),Haimen, Jiangsu 226100, P.R.China
Sichuan Sangao Biochemical Co., Ltd

Contact:+86-28-84874233

Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
SYN Pharma Co., Ltd

Contact:86-21 60347964

Address:No.1304, West Meilong Road, Minhang District, Shanghai, China
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China

Relevant to this article

Ligand-Dependent Site-Selective Suzuki Cross-Coupling of 4-Bromopyrazol-5-yl Triflates

Doi:10.1021/acs.joc.9b01306
(2019)
Rearrangement of oxazolidinethiones to thiazolidinediones or thiazinanediones and their application for the synthesis of chiral allylic ureas and α-methyl-β-amino acids

Doi:10.1016/j.tet.2009.11.035
(2010)
Highly Selective Formation of Cis-Substituted Hydroxylactams via Auxiliary-Controlled Reduction of Imides

Doi:10.1021/jo00272a004
(1989)
Liquid-crystalline self-organization of isocyanide-containing dendrimers induced by coordination to gold(I) fragments

Doi:10.1021/ja909435e
(2010)
Copper-catalyzed addition of water affording highly substituted furan and unusual formation of naphthofuran ring from 3-(1-alkenyl)-2-alkene-1-al

Doi:10.1016/j.tetlet.2009.10.125
(2010)
New chromane-based derivatives as inhibitors of mycobacterium tuberculosis salicylate synthase (mbti): Preliminary biological evaluation and molecular modeling studies

Doi:10.3390/molecules23071506
(2018)

Article Doi