Synthesis and Antiinflammatory and Analgesic Activity of 5-Aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolopyrrole-1-carboxylic Acids and 1-Methyl-4-(methylthio)-5-aroylpyrrole-2-acetic Acids

DOI: 10.1021/jm00126a010

Source and publish data:

Journal of Medicinal Chemistry p. 1202 - 1207 (1989)

Update date:2022-08-02

Topics:

Authors:

Muchowski, Joseph M.

Galeazzi, Edvige

Greenhouse, Robert

Guzman, Angel

Perez, Virginia

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00126a010

5-Aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole-1-carboxylic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids were synthesized and assayed as antiinflammatory and analgesic agents.The majority of these compounds exhibit a surpri

Full text of DOI:10.1021/jm00126a010

Products guided by the article

Product name:N,N-dimethyl-4-cyclopropylbenzamide

Cas No:121193-12-2

R&D Labs maybe for 121193-12-2

EnBridge PharmTech Co., Ltd.

website:http://www.enbridgepharm.com

Contact:+86-510-83591909

Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.

Contact:13861062998

Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
Shanghai TBBMed Co.,Ltd

website:http://www.tbbmed.com

Contact:86--21-50498136

Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.

Contact:+86-(574)-81110986

Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo

Relevant to this article

Biopharmaceutical study on the oral and rectal administrations of enamine prodrugs of amino acid-like β-lactam antibiotics in rabbits

Doi:10.1248/cpb.29.1986
(1981)
Synthesis of 3-Substituted 2-Arylpyridines via Cu/Pd-Catalyzed Decarboxylative Cross-Coupling of Picolinic Acids with (Hetero)Aryl Halides

Doi:10.1021/acs.joc.7b00046
(2017)
Polyphosphoric acid-mediated, One-Pot, novel reactions to build polymethoxyarylnaphthalene lignans

Doi:10.1080/00397910902978023
(2010)
Cytotoxic activity of 3-(5-phenyl-3H-[1,2,4]dithiazol-3-yl)chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides

Doi:10.1016/j.ejmech.2009.11.001
(2010)
Effect of structural factors and solvent nature in bromination of anilines

Doi:10.1134/S1070427209090122
(2009)
Unprecedented 'ring transformation-rearrangement' of pyran-2-ones into 5,6-dihydropyran-2-ones through insertion of acetol

Doi:10.1016/j.tetlet.2009.12.051
(2010)

Article Doi