Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents

DOI: 10.1016/j.bmc.2009.12.048

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1117 - 1123 (2010)

Update date:2022-08-04

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Authors:

Lv, Peng-Cheng

Wang, Kai-Rui

Li, Qing-Shan

Chen, Jin

Sun, Juan

Zhu, Hai-Liang

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Article abstract of DOI:10.1016/j.bmc.2009.12.048

A series of long-chain derivatives of chrysin (compounds 3-22) were synthesized to evaluate for their antiproliferative activities against the human liver cancer cell line HT-29 and EGFR inhibitory activity. Among the compounds tested, compounds hexadecyl

Full text of DOI:10.1016/j.bmc.2009.12.048

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