Synthesis of 1,4-Thiazepine Derivatives Having Angiotensin-Converting Enzyme Inhibitory Property

DOI: 10.1246/cl.1989.137

Source and publish data:

Chemistry Letters p. 137 - 140 (1989)

Update date:2022-08-05

Topics:

Authors:

Yanagisawa, Hiroaki

Ishihara, Sadao

Ando, Akiko

Kanazaki, Takuro

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1989.137

Reduction of (6R)-6-amino-6,7-dihydro-2-thienyl-1,4-thiazepin-5(4H)-one derivatives with Mg-MeOH gave the corresponding perhydrothiazepinones.Protection with trityl group at the 6-amino group gave predominantly the 2S,6R isomer which was converted to the

Full text of DOI:10.1246/cl.1989.137

Products guided by the article

Product name:(2R,6R)-2-Thiophen-2-yl-6-(trityl-amino)-[1,4]thiazepan-5-one

Cas No:121740-49-6

R&D Labs maybe for 121740-49-6

Chengdu Push Bio-technology Co., Ltd

Contact:--

Address:No.8 Wuke West Second Road, Wuhou
Ji'an Hairui Natural Plant Co. Ltd.

Contact:0796-8105528

Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China
Afine Chemicals Limited

website:http://www.afinechem.com

Contact:+86-571-85134551

Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

Relevant to this article

Catalyst-free aqueous multicomponent domino reactions from formaldehyde and 1,3-dicarbonyl derivatives

Doi:10.1039/b913846c
(2009)
A biomimetic approach to the synthesis of a mycolic acid motif

Doi:10.1016/j.tetlet.2009.12.105
(2010)
A mild, catalytic and efficient Nazarov cyclization mediated by phosphomolybdic acid

Doi:10.1039/b918137g
(2010)
Highly Enantioselective Hydrogenation of α-Arylmethylene Cycloalkanones Catalyzed by Iridium Complexes of Chiral Spiro Aminophosphine Ligands

Doi:10.1021/ja100652f
(2010)
1,2-, 1,7- And l,12-dicarba-closo-dodecaborane(12) derivatives revisited by¹³C NMR spectroscopy and DFT calculations. First observation of isotopeInduced chemical shifts¹?^10/11B( ¹³C), and the signs and magnitud

Doi:10.1002/zaac.200900022
(2009)
Enantioselective synthesis of cyclopentene carbaldehydes by a direct multicatalytic cascade sequence: Carbocyclization of aldehydes with alkynes

Doi:10.1002/chem.200903405
(2010)

Article Doi