1-Substituted-1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-alkyloximes as novel orally active and long-lasting muscarinic cholinergic agonists

DOI: 10.1016/0223-5234(92)90186-5

Source and publish data:

European Journal of Medicinal Chemistry p. 519 - 526 (1992)

Update date:2022-07-29

Topics:

Authors:

Toja, E Toja, E

Bonetti, C

Butti, A

Hunt, P Hunt, P

Fortin, M

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(92)90186-5

Our previous attempts to design muscarinic agonists related to arecoline with the prerequisites for clinical use were successful with the discovery of 1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-methyloxime hydrochloride, RU 35963, and structurally rela

Full text of DOI:10.1016/0223-5234(92)90186-5

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