Design, synthesis and pharmacological evaluation of a novel mTOR-targeted anti-EV71 agent

DOI: 10.1016/j.ejmech.2019.04.048

Source and publish data:

European Journal of Medicinal Chemistry p. 172 - 186 (2019)

Update date:2022-07-30

Topics:

Authors:

Hao, Tianlong

Li, Yuexiang

Fan, Shiyong

Li, Wei Li, Wei

Wang, Shixu

Li, Song

Cao, Ruiyuan

Zhong, Wu

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Article abstract of DOI:10.1016/j.ejmech.2019.04.048

Due to the limitations of existing anti-EV71 targets, we have been eager to discover a new anti-EV71 agent based on mTOR (the mammalian target of rapamycin), which is an important target for finding antiviral agents based on host cells. Torin2 is a second

Full text of DOI:10.1016/j.ejmech.2019.04.048

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