Directed Metalation of N,N-Diethylbenzamides. Silylated Benzamides for the Synthesis of Naturally Occurring pero-Methylanthraquinones and peri-Methyl Polycyclic Aromatic Hydrocarbons

Article abstract of DOI:10.1021/jo00279a029

Efficient methodologies based on directed ortho metalation, fluoride-induced carbodesilylation, and metal-halogen exchange processes (Scheme I) are reported for the synthesis of peri-methyl-substituted anthraquinone natural products 5 and polycyclic aroma