Sterically Hindered 5,11-Dicarbo Analogues of Clozapine as Potential Chiral Antipsychotic Agents

DOI: 10.1021/jm00130a006

Source and publish data:

Journal of Medicinal Chemistry p. 2261 - 2268 (1989)

Update date:2022-07-29

Topics:

Authors:

Rupard, J. Howard

Paulis, Tomas de

Janowsky, Aaron

Smith, Howard E.

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Article abstract of DOI:10.1021/jm00130a006

Sterically hindered 5,11-dicarbo analogues of clozapine were prepared as potential chiral antipsychotic agents, with the possibility that for a particular analogue the antispychotic activity of clozapine may reside in one enantiomer of the analogue wherea

Full text of DOI:10.1021/jm00130a006

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