ENZYMES AS SELECTIVE REAGENTS IN ORGANIC SYNTHESIS: ENANTIOSELECTIVE PREPARATION OF "ASYMMETRIZED tris(HYDROXYMETHYL)METHANE"

Article abstract of DOI:10.1016/S0040-4039(00)99101-9

A new C-4 chiral building block, that is a tris(hydroxymethyl)methane derivative where the three equivalent hydroxymethyl groups have been differentiated <(THYM)^*>, was prepared with excellent enantioselection, through PPL catalysed monohydroly