Synthesis of α,ω-Diamino Acids via Amidocarbonylation Reaction: Novel Synthesis of Lysine, Ornithine, and Their Analogs

Article abstract of DOI:10.1246/bcsj.64.613

α,ω-Diamino acid derivatives, such as lysine and ornithine, were synthesized via amidocarbonylation (cobalt-catalyzed formation of N-acyl α-amino acid from aldehyde, amide and carbon monoxide) of ω-(phthalimido)alkanals in good yield.The phthalimido group